Sara Molesworth-Kenyon, Ph.D.
Professor of Biology & Co-Director of Microbiology Certificate Program
678-839-4028
smoleswo@westga .edu
Biology Building - Room 285
Office Hours
by appointment
I graduated from the University of Surrey with an honours degree in Microbiology in 1994. My final dissertation was on the sequencing of the genome of Kyasanur Forest Disease virus. During my undergraduate degree I spent a year in industry with SmithKline Beecham Pharmaceuticals researching Post Beta Lactamase effect and antibiotic resistance to support the dosing regimen for the drug Augmentin. After my bachelors degree I entered the lab of Andrew Morgan at the University of Bristol to study Epstein-Barr virus gene expression with a focus on the attachment protein gH and it's chaperone protein gL. I obtained my PhD in Virology in 1997. After Graduate school I accepted a 5 year Research Fellow position at the University of Missouri, Kansas City, and moved to the United States. My research changed to focus on both virology and immunology with a move to the University of South Alabama and the lab of Dr. Robert Lausch, a founding scientist in the field of Herpes virology.
I spent 10 years in the post doctoral research of the genetics of Epstein-Barr Virus and immune response to Herpes Simplex virus infection. When I joined the faculty at UWG in 2009 I continued to work within the fields of immunology and virology on research into the inflammatory response to HSV-1 infections of the human cornea.
My current research Interests :
I have focused my interests on the neutrophil. Specifically, the involvement of neutrophils in the production of T cell recruiting chemokines during Herpes simplex virus (HSV-1) infection of human corneas. In the lab we use a novel ex vivo model for HSV-1 corneal infection in which chemokine secretion by the corneal cells and neutrophils may be studied. During experiments we use human corneal tissue supplied by the Georgia Eye Bank, Inc. and neutrophils purified from donated human blood. Additionally, genetically modified knock out mice are used to support the findings of the human corneal work. These mice are bred with specific genes deleted and so lack the ability to produce certain immunologically important proteins. Knock out mice enable to study of the role of an individual protein within the inflammatory cascade produced in response to Herpes simplex virus infection.
I am committed to training undergraduate and masters students at UWG. I have been awarded multiple intramural grants from my College and the Provost to support student research. Research has been presented at meetings of the American Society for microbiology and published in international peer reviewed journals. Working with undergraduate students within one of only two biohazard level II laboratories here at UWG requires a high level of commitment to train students in protocols and safety. It provides me with great satisfaction when my students successfully graduate to medical college, allied health, or research positions having completed a clinically orientated research experience.
- B.Sc., Microbiology, University of Surrey, UK, 1993
- Ph.D., Virology, University of Bristol, UK, 1997
- BIOL-1010L (Fundamentals of Biology Lab)
- BIOL-1013 (Biol of AIDS & Infect Disease)
- BIOL-1107L (Principles of Biology I Lab)
- BIOL-2030L (Medical Microbiology Lab)
- BIOL-2260 (Foundations of Microbiology)
- BIOL-2260L (Found of Microbiology Lab)
- BIOL-3310 (Microbiology)
- BIOL-4727 (Essentials of Immunology)
- BIOL-4729 (Medical Virology)
- BIOL-4730 (Emerging Pathogens)
- BIOL-4986 (MicrobioInternshpAsymmetryTech)
- BIOL-5727 (Essentials of Immunology)
- BIOL-5729 (Medical Virology-Graduate)
- BIOL-5730 (Emerging Pathogens)
- BIOL-6984 (Graduate Biology Seminar)
Spring 2025 Sections
- BIOL-2260 (Foundations of Microbiology) Section: 01 external Syllabus via Concourse External Resource
- BIOL-2260L (Found of Microbiology Lab) Section: 01 external Syllabus via Concourse External Resource
- BIOL-2260L (Found of Microbiology Lab) Section: 02 external Syllabus via Concourse External Resource
- BIOL-3310 (Microbiology) Section: 02 external Syllabus via Concourse External Resource
Fall 2024 Sections
- BIOL-1010L (Fundamentals of Biology Lab) Section: 01 external Syllabus via Concourse External Resource
- BIOL-3310 (Microbiology) Section: 02 external Syllabus via Concourse External Resource
- BIOL-4729 (Medical Virology) Section: 01W external Syllabus via Concourse External Resource
- BIOL-4986 (Microbiology Internship) Section: E01 external Syllabus via Concourse External Resource
- BIOL-5729 (Medical Virology) Section: 01 external Syllabus via Concourse External Resource
Summer 2024 Sections
- BIOL-1013 (Biol of AIDS & Infect Disease) Section: E01 external Syllabus via Concourse External Resource
- BIOL-4730 (Emerging Pathogens) Section: 1DW external Syllabus via Concourse External Resource
- BIOL-5730 (Emerging Pathogens) Section: E01 external Syllabus via Concourse External Resource
Spring 2024 Sections
- BIOL-2260 (Foundations of Microbiology) Section: 01 external Syllabus via Concourse External Resource
- BIOL-2260L (Found of Microbiology Lab) Section: 01 external Syllabus via Concourse External Resource
- BIOL-2260L (Found of Microbiology Lab) Section: 02 external Syllabus via Concourse External Resource
- BIOL-2260L (Found of Microbiology Lab) Section: 03 external Syllabus via Concourse External Resource
- BIOL-3310 (Microbiology) Section: 02 external Syllabus via Concourse External Resource
- BIOL-4986 (Microbiology Tech) Section: 02 external Syllabus via Concourse External Resource
Fall 2023 Sections
- BIOL-1010L (Fundamentals of Biology Lab) Section: 01 external Syllabus via Concourse External Resource
- BIOL-1107L (Principles of Biology I Lab) Section: 04 external Syllabus via Concourse External Resource
- BIOL-3310 (Microbiology) Section: 02 external Syllabus via Concourse External Resource
- BIOL-4727 (Essentials of Immunology) Section: 01W external Syllabus via Concourse External Resource
- BIOL-5727 (Essentials of Immunology) Section: 01 external Syllabus via Concourse External Resource
Summer 2023 Sections
- BIOL-1013 (Biol of AIDS & Infect Disease) Section: E01 external Syllabus via Concourse External Resource
- BIOL-4730 (Emerging Pathogens) Section: 1DW external Syllabus via Concourse External Resource
- BIOL-5730 (Emerging Pathogens) Section: E01 external Syllabus via Concourse External Resource
Spring 2023 Sections
- BIOL-2030L (Medical Microbiology Lab) Section: 03 external Syllabus via Concourse External Resource
- BIOL-3310 (Microbiology) Section: 02 external Syllabus via Concourse External Resource
- BIOL-4729 (Medical Virology) Section: 01W external Syllabus via Concourse External Resource
- BIOL-4986 (MicrobioInternshpAsymmetryTech) Section: E01 external Syllabus via Concourse External Resource
- BIOL-5729 (Medical Virology) Section: 01 external Syllabus via Concourse External Resource
Fall 2022 Sections
- BIOL-3310 (Microbiology) Section: 01 external Syllabus via Concourse External Resource
- BIOL-4727 (Essentials of Immunology) Section: 01W external Syllabus via Concourse External Resource
- BIOL-5727 (Essentials of Immunology) Section: 01 external Syllabus via Concourse External Resource
- BIOL-6984 (Graduate Biology Seminar) Section: 01 external Syllabus via Concourse External Resource
Summer 2022 Sections
- BIOL-1013 (Biol of AIDS & Infect Disease) Section: E01 external Syllabus via Concourse External Resource
- BIOL-4730 (Emerging Pathogens) Section: 1DW external Syllabus via Concourse External Resource
- BIOL-5730 (Emerging Pathogens) Section: E01 external Syllabus via Concourse External Resource
Spring 2022 Sections
- BIOL-3310 (Microbiology) Section: 02 external Syllabus via Concourse External Resource
- BIOL-4729 (Medical Virology) Section: 01W external Syllabus via Concourse External Resource
- BIOL-5729 (Medical Virology) Section: 01 external Syllabus via Concourse External Resource
Fall 2021 Sections
- BIOL-3310 (Microbiology) Section: 01 external Syllabus via Concourse External Resource
- BIOL-4727 (Essentials of Immunology) Section: 01W external Syllabus via Concourse External Resource
- BIOL-5727 (Essentials of Immunology) Section: 01 external Syllabus via Concourse External Resource
Summer 2021 Sections
- BIOL-1013 (Biol of AIDS & Infect Disease) Section: E01 external Syllabus via Concourse External Resource
- BIOL-4730 (Emerging Pathogens) Section: 1DW external Syllabus via Concourse External Resource
- BIOL-5730 (Emerging Pathogens) Section: E01 external Syllabus via Concourse External Resource
Spring 2021 Sections
- BIOL-3310 (Microbiology) Section: E02 external Syllabus via Concourse External Resource
- BIOL-4729 (Medical Virology) Section: 1DW external Syllabus via Concourse External Resource
- BIOL-5729 (Medical Virology-Graduate) Section: E01 external Syllabus via Concourse External Resource
Fall 2020 Sections
- BIOL-3310 (Microbiology) Section: E01 external Syllabus via Concourse External Resource
- BIOL-4727 (Essentials of Immunology) Section: E01 external Syllabus via Concourse External Resource
- BIOL-5727 (Essentials of Immunology) Section: E01 external Syllabus via Concourse External Resource
S.J. Molesworth, C.M. Lake, C.M. Borza, S.M. Turk and L.M. Hutt-Fletcher. Journal of Virology. 74(14):6324-6332. 2000.
C.E. Thorburn, S.J. Molesworth, R. Sutherland and S. Rittenhouse. Antimicrobial Agents and Chemotherapy. 40 (12):2796-2801. 1996.
S. Molesworth-Kenyon, J.E. Oakes and R.N. Lausch. Journal of Leukocyte Biology. 77:552-559. 2005.
S. Molesworth-Kenyon, *A. Mates, R. Yin, J.E. Oakes and R.N. Lausch. Virology. 333:1-9. 2005.
T.M. Tumpey, R. Fenton, S. Molesworth-Kenyon, J.E. Oakes and R.N .Lausch. Journal of Virology. 76(16):8050-8057. 2002.
R.R. Fenton, S. Molesworth-Kenyon, J.E. Oakes and R.N. Lausch. Investigative Ophthalmology and Visual Science. 43(3):737-743. 2002.
C.M. Lake, S.J. Molesworth and L.M. Hutt-Fletcher. Journal of Virology. 72(7):5559-5564. 1998.
1. Hirose S, Wang S, Jaggi U, Matundan HH, Kato M, Song XY, Molesworth-Kenyon SJ, Lausch RN, Ghiasi H. IL-17A expression by both T cells and non-T cells contribute to HSV-IL-2-induced CNS demyelination. Front Immunol. 2023 Feb 2;14:1102486. doi: 10.3389/fi
Curr Eye Res. 2020;10.1080/02713683.2020.1803921. doi:10.1080/02713683.2020.1803921
2. Young ES, Butler JD, Molesworth-Kenyon SJ, and Kenyon W (2023) Biofilm-Mediated Fragmentation and Degradation of Microcrystalline Cellulose by Cellulomonas flavigena KU (ATCC 53703). Current Microbiology vol. 80, article 200. https://doi.org/10.1007/s
S. J. Molesworth-Kenyon, A. Milam*, A. Rockette*, A. Troupe*, John. E. Oakes and Robert. N. Lausch. Current Eye Research. Sep 10:1-9. 2014. [View Publication (PDF)]
S. Molesworth-Kenyon, *N. Popham, A. Milam, J.E. Oakes and R.N. Lausch. International Journal of Inflammation. Special issue, Ocular Inflammation and Infection. Volume 2012 (2012), Article ID 810359 [View Publication (PDF)]
S. Molesworth-Kenyon, R. Yin, J.E. Oakes and R.N. Lausch. Journal of Leukocyte Biology. 83:401-408. 2008. [View Publication (PDF)]
Microbiology
Skills include, aseptic technique, tissue culture, microscopy, bio- hazardous material handling, ELISA, viral propagation etc.